Felbatol
Brand names,
Felbatol
Analogs
Felbatol
Brand Names Mixture
Felbatol
Chemical_Formula
C11H14N2O4
Felbatol
RX_link
http://www.rxlist.com/cgi/generic3/felbamate.htm
Felbatol
fda sheet
Felbatol
msds (material safety sheet)
Felbatol
Synthesis Reference
No information avaliable
Felbatol
Molecular Weight
238.24 g/mol
Felbatol
Melting Point
151.5 oC
Felbatol
H2O Solubility
Slightly soluble in water
Felbatol
State
Solid
Felbatol
LogP
0.76
Felbatol
Dosage Forms
Tablet; Suspension
Felbatol
Indication
For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.
Felbatol
Pharmacology
Felbamate is an antiepileptic indicated as monotherapy or as an adjunct to other anticonvulsants for the treatment of partial seizures resulting from epilepsy. Receptor-binding studies in vitro indicate that felbamate has weak inhibitory effects on GABA-receptor binding, benzodiazepine receptor binding, and is devoid of activity at the MK-801 receptor binding site of the NMDA receptor-ionophore complex. However, felbamate does interact as an antagonist at the strychnine-insensitive glycine recognition site of the NMDA receptor-ionophore complex.
Felbatol
Absorption
>90%
Felbatol
side effects and Toxicity
LD50=5000 mg/kg (Orally in rats)
Felbatol
Patient Information
Patient Information:
Felmabate can cause severe blood abnormality, hepatic failure and other fatal
conditions. Talk about the risks and side effects with your doctor before taking it.
Do not stop the medication without consulting your doctor. Finish the medication
even if you feel better.
Felbatol
Organisms Affected
Humans and other mammals