Famciclovir
Brand names,
Famciclovir
Analogs
Famciclovir
Brand Names Mixture
Famciclovir
Chemical_Formula
C14H19N5O4
Famciclovir
RX_link
http://www.rxlist.com/cgi/generic3/famciclovir.htm
Famciclovir
fda sheet
Famciclovir
msds (material safety sheet)
Famciclovir
Synthesis Reference
Geen, et al.; Tetrahedron Lett.; 33; 32;4609-4612(1992).
Famciclovir
Molecular Weight
321.332 g/mol
Famciclovir
Melting Point
102-104 oC
Famciclovir
H2O Solubility
No information avaliable
Famciclovir
State
Solid
Famciclovir
LogP
1.566
Famciclovir
Dosage Forms
Tablet
Famciclovir
Indication
For the treatment of acute herpes zoster (shingles). Also for the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
Famciclovir
Pharmacology
Famciclovir is a prodrug that undergoes rapid biotransformation to the active antiviral compound penciclovir. Penciclovir is an anti-viral drug which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). Therefore, herpes viral DNA synthesis and replication are selectively inhibited.
Famciclovir
Absorption
77 %
Famciclovir
side effects and Toxicity
Symptoms of overdose include constipation, diarrhea, dizziness, fatigue, fever, headache, nausea, and vomiting.
Famciclovir
Patient Information
Famciclovir
Organisms Affected
Human Herpes Virus