Famciclovirum [Inn-Latin]
Brand names,
Famciclovirum [Inn-Latin]
Analogs
Famciclovirum [Inn-Latin]
Brand Names Mixture
Famciclovirum [Inn-Latin]
Chemical_Formula
C14H19N5O4
Famciclovirum [Inn-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/famciclovir.htm
Famciclovirum [Inn-Latin]
fda sheet
Famciclovirum [Inn-Latin]
msds (material safety sheet)
Famciclovirum [Inn-Latin]
Synthesis Reference
Geen, et al.; Tetrahedron Lett.; 33; 32;4609-4612(1992).
Famciclovirum [Inn-Latin]
Molecular Weight
321.332 g/mol
Famciclovirum [Inn-Latin]
Melting Point
102-104 oC
Famciclovirum [Inn-Latin]
H2O Solubility
No information avaliable
Famciclovirum [Inn-Latin]
State
Solid
Famciclovirum [Inn-Latin]
LogP
1.566
Famciclovirum [Inn-Latin]
Dosage Forms
Tablet
Famciclovirum [Inn-Latin]
Indication
For the treatment of acute herpes zoster (shingles). Also for the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
Famciclovirum [Inn-Latin]
Pharmacology
Famciclovir is a prodrug that undergoes rapid biotransformation to the active antiviral compound penciclovir. Penciclovir is an anti-viral drug which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). Therefore, herpes viral DNA synthesis and replication are selectively inhibited.
Famciclovirum [Inn-Latin]
Absorption
77 %
Famciclovirum [Inn-Latin]
side effects and Toxicity
Symptoms of overdose include constipation, diarrhea, dizziness, fatigue, fever, headache, nausea, and vomiting.
Famciclovirum [Inn-Latin]
Patient Information
Famciclovirum [Inn-Latin]
Organisms Affected
Human Herpes Virus