FCV
Brand names,
FCV
Analogs
FCV
Brand Names Mixture
FCV
Chemical_Formula
C14H19N5O4
FCV
RX_link
http://www.rxlist.com/cgi/generic3/famciclovir.htm
FCV
fda sheet
FCV
msds (material safety sheet)
FCV
Synthesis Reference
Geen, et al.; Tetrahedron Lett.; 33; 32;4609-4612(1992).
FCV
Molecular Weight
321.332 g/mol
FCV
Melting Point
102-104 oC
FCV
H2O Solubility
No information avaliable
FCV
State
Solid
FCV
LogP
1.566
FCV
Dosage Forms
Tablet
FCV
Indication
For the treatment of acute herpes zoster (shingles). Also for the treatment or suppression of recurrent genital herpes in immunocompetent patients and treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
FCV
Pharmacology
Famciclovir is a prodrug that undergoes rapid biotransformation to the active antiviral compound penciclovir. Penciclovir is an anti-viral drug which has inhibitory activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella zoster virus (VZV). Therefore, herpes viral DNA synthesis and replication are selectively inhibited.
FCV
Absorption
77 %
FCV
side effects and Toxicity
Symptoms of overdose include constipation, diarrhea, dizziness, fatigue, fever, headache, nausea, and vomiting.
FCV
Patient Information
FCV
Organisms Affected
Human Herpes Virus