Ethoxzolamide
Brand names,
Ethoxzolamide
Analogs
Ethoxzolamide
Brand Names Mixture
Ethoxzolamide
Chemical_Formula
C9H10N2O3S2
Ethoxzolamide
RX_link
No information avaliable
Ethoxzolamide
fda sheet
Ethoxzolamide
msds (material safety sheet)
Ethoxzolamide
Synthesis Reference
No information avaliable
Ethoxzolamide
Molecular Weight
258.319 g/mol
Ethoxzolamide
Melting Point
189 oC
Ethoxzolamide
H2O Solubility
40 mg/L
Ethoxzolamide
State
Solid
Ethoxzolamide
LogP
1.218
Ethoxzolamide
Dosage Forms
Tablet (125, 250 mg); Capsule (500mg); Injection (500mg)
Ethoxzolamide
Indication
For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
Ethoxzolamide
Pharmacology
Ethoxzolamide, a sulfonamide, inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. It also decreases carbonic anhydrase in the CNS, increasing the seizure threshold. This reduction in carbonic anhydrase also reduces the intraocular pressure in the eye by decreasing aqueous humor.
Ethoxzolamide
Absorption
Rapidly absorbed with 65% bioavailability
Ethoxzolamide
side effects and Toxicity
No information avaliable
Ethoxzolamide
Patient Information
Ethoxzolamide
Organisms Affected
Humans and other mammals