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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C9H10N2O3S2
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
258.319 g/mol
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Melting Point
189 oC
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H2O Solubility
40 mg/L
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State
Solid
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LogP
1.218
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Dosage Forms
Tablet (125, 250 mg); Capsule (500mg); Injection (500mg)
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Indication
For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
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Pharmacology
Ethoxzolamide, a sulfonamide, inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. It also decreases carbonic anhydrase in the CNS, increasing the seizure threshold. This reduction in carbonic anhydrase also reduces the intraocular pressure in the eye by decreasing aqueous humor.
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Absorption
Rapidly absorbed with 65% bioavailability
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side effects and Toxicity
No information avaliable
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Patient Information
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Organisms Affected
Humans and other mammals