Ethionamide
Brand names,
Ethionamide
Analogs
Ethionamide
Brand Names Mixture
Ethionamide
Chemical_Formula
C14H16N2O2
Ethionamide
RX_link
No information avaliable
Ethionamide
fda sheet
Ethionamide
msds (material safety sheet)
Ethionamide
Synthesis Reference
No information avaliable
Ethionamide
Molecular Weight
244.289 g/mol
Ethionamide
Melting Point
67 oC
Ethionamide
H2O Solubility
63.2 mg/L
Ethionamide
State
Solid
Ethionamide
LogP
2.695
Ethionamide
Dosage Forms
Solution for injection (2 mg/mL)
Ethionamide
Indication
Used in the induction of general anesthesia.
Ethionamide
Pharmacology
Etomidate is a non-barbiturate hypnotic that acts at the level of the reticular-activating system to produce anesthesia. Etomidate is an imidazole compound that appears to depress CNS function via GABA. Duration of action is intermediate between thiopental and methohexital, and recovery from a single dose is rapid with little residual depression. Like the barbiturates and propofol, etomidate is does not induce analgesia. Etomidate induces unconsciousness within one circulation time. Recovery is rapid as a result of extensive redistribution and rapid metabolism.
Ethionamide
Absorption
No information avaliable
Ethionamide
side effects and Toxicity
Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
Ethionamide
Patient Information
No information avaliable
Ethionamide
Organisms Affected
Humans and other mammals