Eprosartan
Eprosartan Brand names, Eprosartan Analogs
Eprosartan Brand Names Mixture
- No information avaliable
Eprosartan Chemical_Formula
C23H24N2O4S
Eprosartan RX_link
http://www.rxlist.com/cgi/generic3/eprosartan.htm
Eprosartan fda sheet
Eprosartan msds (material safety sheet)
Eprosartan Synthesis Reference
No information avaliable
Eprosartan Molecular Weight
424.514 g/mol
Eprosartan Melting Point
248-250oC (mesylate form)
Eprosartan H2O Solubility
Insoluble (mesylate form)
Eprosartan State
Solid
Eprosartan LogP
4.283
Eprosartan Dosage Forms
Tablet (400 mg or 600 mg)
Eprosartan Indication
For the treatment of hypertension.
Eprosartan Pharmacology
Eprosartan inhibits the pharmacologic effects of angiotensin II. As angiotensin II is a vasoconstrictor, this inhibition effectively lowers blood pressure.
Eprosartan Absorption
Absolute bioavailability following a single 300 mg oral dose of eprosartan is approximately 13%. Administering eprosartan with food delays absorption.
Eprosartan side effects and Toxicity
There was no mortality in rats and mice receiving oral doses of up to 3000 mg eprosartan/kg and in dogs receiving oral doses of up to 1000 mg eprosartan/kg.
Eprosartan Patient Information
Eprosartan Organisms Affected
Humans and other mammals
