Relpax
Brand names,
Relpax
Analogs
Relpax
Brand Names Mixture
Relpax
Chemical_Formula
C23H24N2O4S
Relpax
RX_link
http://www.rxlist.com/cgi/generic3/eprosartan.htm
Relpax
fda sheet
Relpax
msds (material safety sheet)
Relpax
Synthesis Reference
No information avaliable
Relpax
Molecular Weight
424.514 g/mol
Relpax
Melting Point
248-250oC (mesylate form)
Relpax
H2O Solubility
Insoluble (mesylate form)
Relpax
State
Solid
Relpax
LogP
4.283
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Dosage Forms
Tablet (400 mg or 600 mg)
Relpax
Indication
For the treatment of hypertension.
Relpax
Pharmacology
Eprosartan inhibits the pharmacologic effects of angiotensin II. As angiotensin II is a vasoconstrictor, this inhibition effectively lowers blood pressure.
Relpax
Absorption
Absolute bioavailability following a single 300 mg oral dose of eprosartan is approximately 13%. Administering eprosartan with food delays absorption.
Relpax
side effects and Toxicity
There was no mortality in rats and mice receiving oral doses of up to 3000 mg eprosartan/kg and in dogs receiving oral doses of up to 1000 mg eprosartan/kg.
Relpax
Patient Information
Relpax
Organisms Affected
Humans and other mammals