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Dofetilide Brand names, Dofetilide Analogs

Dofetilide Brand Names Mixture

  • No information avaliable

Dofetilide Chemical_Formula


Dofetilide RX_link

Dofetilide fda sheet

Dofetilide FDA

Dofetilide msds (material safety sheet)

Dofetilide Synthesis Reference

No information avaliable

Dofetilide Molecular Weight

441.567 g/mol

Dofetilide Melting Point

No information avaliable

Dofetilide H2O Solubility

No information avaliable

Dofetilide State


Dofetilide LogP


Dofetilide Dosage Forms


Dofetilide Indication

For the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fibrillation/atrial flutter of greater than one week duration who have been converted to normal sinus rhythm

Dofetilide Pharmacology

Dofetilide is an antiarrhythmic drug with Class III (cardiac action potential duration prolonging) properties and is indicated for the maintenance of normal sinus rhythm. Dofetilide increases the monophasic action potential duration in a predictable, concentration-dependent manner, primarily due to delayed repolarization. At concentrations covering several orders of magnitude, Dofetilide blocks only IKr with no relevant block of the other repolarizing potassium currents (e.g., IKs, IK1). At clinically relevant concentrations, Dofetilide has no effect on sodium channels (associated with Class I effect), adrenergic alpha-receptors, or adrenergic beta-receptors.

Dofetilide Absorption


Dofetilide side effects and Toxicity

No information avaliable

Dofetilide Patient Information

No information avaliable

Dofetilide Organisms Affected

Humans and other mammals