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Dofetilida Brand names, Dofetilida Analogs

Dofetilida Brand Names Mixture

  • No information avaliable

Dofetilida Chemical_Formula


Dofetilida RX_link

Dofetilida fda sheet

Dofetilida FDA

Dofetilida msds (material safety sheet)

Dofetilida Synthesis Reference

No information avaliable

Dofetilida Molecular Weight

441.567 g/mol

Dofetilida Melting Point

No information avaliable

Dofetilida H2O Solubility

No information avaliable

Dofetilida State


Dofetilida LogP


Dofetilida Dosage Forms


Dofetilida Indication

For the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fibrillation/atrial flutter of greater than one week duration who have been converted to normal sinus rhythm

Dofetilida Pharmacology

Dofetilide is an antiarrhythmic drug with Class III (cardiac action potential duration prolonging) properties and is indicated for the maintenance of normal sinus rhythm. Dofetilide increases the monophasic action potential duration in a predictable, concentration-dependent manner, primarily due to delayed repolarization. At concentrations covering several orders of magnitude, Dofetilide blocks only IKr with no relevant block of the other repolarizing potassium currents (e.g., IKs, IK1). At clinically relevant concentrations, Dofetilide has no effect on sodium channels (associated with Class I effect), adrenergic alpha-receptors, or adrenergic beta-receptors.

Dofetilida Absorption


Dofetilida side effects and Toxicity

No information avaliable

Dofetilida Patient Information

No information avaliable

Dofetilida Organisms Affected

Humans and other mammals