Diphtheria toxin precursor
Diphtheria toxin precursor Brand names, Diphtheria toxin precursor Analogs
Diphtheria toxin precursor Brand Names Mixture
- No information avaliable
Diphtheria toxin precursor Chemical_Formula
C2560H4042N678O799S17
Diphtheria toxin precursor RX_link
http://www.rxlist.com/cgi/generic2/denileukin.htm
Diphtheria toxin precursor fda sheet
Diphtheria toxin precursor msds (material safety sheet)
Diphtheria toxin precursor Synthesis Reference
No information avaliable
Diphtheria toxin precursor Molecular Weight
57647.3
Diphtheria toxin precursor Melting Point
No information avaliable
Diphtheria toxin precursor H2O Solubility
No information avaliable
Diphtheria toxin precursor State
Liquid
Diphtheria toxin precursor LogP
-0.301
Diphtheria toxin precursor Dosage Forms
Solution (IV Infusion)
Diphtheria toxin precursor Indication
For treatment of cutaneous T-cell lymphoma
Diphtheria toxin precursor Pharmacology
Denileukin diftitox (Ontak) directs the cytocidal action of diphtheria toxin to cells which express the IL-2 receptor. The human IL-2 receptor exists in three forms, low (CD25), intermediate (CD122/CD132) and high (CD25/CD122/CD132) affinity. Malignant cells expressing one or more of the subunits of the IL-2 receptor are found in certain leukemias and lymphomas including cutaneous T-cell lymphoma (CTCL). Ontak interacts with the high affinity IL-2 receptor on the cell surface and inhibits cellular protein synthesis, resulting in cell death within hours.
Diphtheria toxin precursor Absorption
No information avaliable
Diphtheria toxin precursor side effects and Toxicity
No information avaliable
Diphtheria toxin precursor Patient Information
No information avaliable
Diphtheria toxin precursor Organisms Affected
Humans and other mammals
