Digoxin
Digoxin Brand names, Digoxin Analogs
Digoxin Brand Names Mixture
- No information avaliable
Digoxin Chemical_Formula
C41H64O14
Digoxin RX_link
http://www.rxlist.com/cgi/generic/dig.htm
Digoxin fda sheet
Digoxin msds (material safety sheet)
Digoxin Synthesis Reference
S. Smith, J. Chem. Soc. 1930, 508
Digoxin Molecular Weight
780.938 g/mol
Digoxin Melting Point
248-250 oC
Digoxin H2O Solubility
Insoluble
Digoxin State
Solid
Digoxin LogP
1.969
Digoxin Dosage Forms
Tablet; Capsule; Injection
Digoxin Indication
For the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
Digoxin Pharmacology
Digoxin, a cardiac glycoside similar to digitoxin, is used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.
Digoxin Absorption
Absorption of digoxin from the elixir pediatric formulation has been demonstrated to be 70% to 85% complete (90% to 100% from the capsules, and 60% to 80% for tablets).
Digoxin side effects and Toxicity
Toxicity includes ventricular tachycardia or ventricular fibrillation, or progressive bradyarrhythmias, or heart block. LD50 = 7.8 mg/kg (orally in mice).
Digoxin Patient Information
Digoxin is used for the treatment of congestive heart failure and for irregular heartbeat. Notify your physician if you are pregnant or nursing. Do not stop taking digoxin without talking with your physician. Digoxin may be taken with or without food. It should be taken at approximately the same time each morning. Do not take over-the-counter antacids, cough, cold, allergy or diet medications without notifying your physician and pharmacist. Notify your physician if you develop an irregular heartbeat, trouble breathing, skin rash, nausea, diarrhea, blurred or yellow vision, or unusual weakness or tiredness.
Digoxin Organisms Affected
Humans and other mammals
