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Dermovate Brand names, Dermovate Analogs

Dermovate Brand Names Mixture

  • No information avaliable

Dermovate Chemical_Formula


Dermovate RX_link

Dermovate fda sheet

Dermovate FDA

Dermovate msds (material safety sheet)

Dermovate MSDS

Dermovate Synthesis Reference

No information avaliable

Dermovate Molecular Weight

466.97 g/mol

Dermovate Melting Point

195.5-197 oC

Dermovate H2O Solubility

3.86 mg/L

Dermovate State


Dermovate LogP


Dermovate Dosage Forms

Foam (0.05%) and ointment (usp 0.05%, supplied in 15 g, 30 g, and 45 g tubes)

Dermovate Indication

For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.

Dermovate Pharmacology

Like other topical corticosteroids, clobetasol has anti-inflammatory, antipruritic, and vasoconstrictive properties. It is a very high potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.

Dermovate Absorption

Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.

Dermovate side effects and Toxicity

Oral LD50 in rat and mouse is >3000 mg/kg. Topically applied clobetasol can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

Dermovate Patient Information

Dermovate Organisms Affected

Humans and other mammals