Clobetasol Propionate en es it fr

Clobetasol Propionate Brand names, Clobetasol Propionate Analogs

Clobetasol Propionate Brand Names Mixture

  • No information avaliable

Clobetasol Propionate Chemical_Formula

C25H32ClFO5

Clobetasol Propionate RX_link

http://www.rxlist.com/cgi/generic/olux.htm

Clobetasol Propionate fda sheet

Clobetasol_Propionate FDA

Clobetasol Propionate msds (material safety sheet)

Clobetasol_Propionate MSDS

Clobetasol Propionate Synthesis Reference

No information avaliable

Clobetasol Propionate Molecular Weight

466.97 g/mol

Clobetasol Propionate Melting Point

195.5-197 oC

Clobetasol Propionate H2O Solubility

3.86 mg/L

Clobetasol Propionate State

Solid

Clobetasol Propionate LogP

3.588

Clobetasol Propionate Dosage Forms

Foam (0.05%) and ointment (usp 0.05%, supplied in 15 g, 30 g, and 45 g tubes)

Clobetasol Propionate Indication

For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.

Clobetasol Propionate Pharmacology

Like other topical corticosteroids, clobetasol has anti-inflammatory, antipruritic, and vasoconstrictive properties. It is a very high potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.

Clobetasol Propionate Absorption

Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.

Clobetasol Propionate side effects and Toxicity

Oral LD50 in rat and mouse is >3000 mg/kg. Topically applied clobetasol can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

Clobetasol Propionate Patient Information

Clobetasol Propionate Organisms Affected

Humans and other mammals