Decamethonium
Brand names,
Decamethonium
Analogs
Decamethonium
Brand Names Mixture
Decamethonium
Chemical_Formula
C16H38N2
Decamethonium
RX_link
No information avaliable
Decamethonium
fda sheet
Decamethonium
msds (material safety sheet)
Decamethonium
Synthesis Reference
No information avaliable
Decamethonium
Molecular Weight
258.486 g/mol
Decamethonium
Melting Point
268-270 oC
Decamethonium
H2O Solubility
Substantial
Decamethonium
State
Solid
Decamethonium
LogP
No information avaliable
Decamethonium
Dosage Forms
No information avaliable
Decamethonium
Indication
For use as a skeletal muscle relaxant
Decamethonium
Pharmacology
Decamethonium acts as a depolarizing muscle relaxant or neuromuscular blocking agent. It acts as an agonist of nicotinic acetycholine receptors in the motor endplate and causes depolarization. This class of drugs has its effect at the neuromuscular junction by preventing the effects of acetylcholine. Normally, when a nerve stimulus acts to contract a muscle, it releases acetylcholine. The binding of this acetylcholine to receptors causes the muscle to contract. Muscle relaxants play an important role in anesthesia even though they don't provide any pain relief or produce unconsciousness.
Decamethonium
Absorption
Rapidly absorbed.
Decamethonium
side effects and Toxicity
LD50=190 mg/kg (orally in mice). Prolonged apnoea, neuromuscular paralysis and cardiac arrest may occur.
Decamethonium
Patient Information
No information avaliable
Decamethonium
Organisms Affected
Humans and other mammals