Syncurine
Brand names,
Syncurine
Analogs
Syncurine
Brand Names Mixture
Syncurine
Chemical_Formula
C16H38N2
Syncurine
RX_link
No information avaliable
Syncurine
fda sheet
Syncurine
msds (material safety sheet)
Syncurine
Synthesis Reference
No information avaliable
Syncurine
Molecular Weight
258.486 g/mol
Syncurine
Melting Point
268-270 oC
Syncurine
H2O Solubility
Substantial
Syncurine
State
Solid
Syncurine
LogP
No information avaliable
Syncurine
Dosage Forms
No information avaliable
Syncurine
Indication
For use as a skeletal muscle relaxant
Syncurine
Pharmacology
Decamethonium acts as a depolarizing muscle relaxant or neuromuscular blocking agent. It acts as an agonist of nicotinic acetycholine receptors in the motor endplate and causes depolarization. This class of drugs has its effect at the neuromuscular junction by preventing the effects of acetylcholine. Normally, when a nerve stimulus acts to contract a muscle, it releases acetylcholine. The binding of this acetylcholine to receptors causes the muscle to contract. Muscle relaxants play an important role in anesthesia even though they don't provide any pain relief or produce unconsciousness.
Syncurine
Absorption
Rapidly absorbed.
Syncurine
side effects and Toxicity
LD50=190 mg/kg (orally in mice). Prolonged apnoea, neuromuscular paralysis and cardiac arrest may occur.
Syncurine
Patient Information
No information avaliable
Syncurine
Organisms Affected
Humans and other mammals