Decamethonum
Decamethonum Brand names, Decamethonum Analogs
Decamethonum Brand Names Mixture
- No information avaliable
Decamethonum Chemical_Formula
C16H38N2
Decamethonum RX_link
No information avaliable
Decamethonum fda sheet
Decamethonum msds (material safety sheet)
Decamethonum Synthesis Reference
No information avaliable
Decamethonum Molecular Weight
258.486 g/mol
Decamethonum Melting Point
268-270 oC
Decamethonum H2O Solubility
Substantial
Decamethonum State
Solid
Decamethonum LogP
No information avaliable
Decamethonum Dosage Forms
No information avaliable
Decamethonum Indication
For use as a skeletal muscle relaxant
Decamethonum Pharmacology
Decamethonium acts as a depolarizing muscle relaxant or neuromuscular blocking agent. It acts as an agonist of nicotinic acetycholine receptors in the motor endplate and causes depolarization. This class of drugs has its effect at the neuromuscular junction by preventing the effects of acetylcholine. Normally, when a nerve stimulus acts to contract a muscle, it releases acetylcholine. The binding of this acetylcholine to receptors causes the muscle to contract. Muscle relaxants play an important role in anesthesia even though they don't provide any pain relief or produce unconsciousness.
Decamethonum Absorption
Rapidly absorbed.
Decamethonum side effects and Toxicity
LD50=190 mg/kg (orally in mice). Prolonged apnoea, neuromuscular paralysis and cardiac arrest may occur.
Decamethonum Patient Information
No information avaliable
Decamethonum Organisms Affected
Humans and other mammals
