DFOM
Brand names,
DFOM
Analogs
DFOM
Brand Names Mixture
DFOM
Chemical_Formula
C20H29N3O2
DFOM
RX_link
No information avaliable
DFOM
fda sheet
DFOM
msds (material safety sheet)
DFOM
Synthesis Reference
No information avaliable
DFOM
Molecular Weight
343.463 g/mol
DFOM
Melting Point
99-101oC (HCl salt)
DFOM
H2O Solubility
42 mg/L
DFOM
State
Solid
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LogP
3.588
DFOM
Dosage Forms
Ointment
DFOM
Indication
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
DFOM
Pharmacology
Dibucaine is an amide-type local anesthetic, similar to lidocaine.
DFOM
Absorption
In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.
DFOM
side effects and Toxicity
Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
DFOM
Patient Information
No information avaliable
DFOM
Organisms Affected
Humans and other mammals