DFO
DFO Brand names, DFO Analogs
DFO Brand Names Mixture
- No information avaliable
DFO Chemical_Formula
C20H29N3O2
DFO RX_link
No information avaliable
DFO fda sheet
DFO msds (material safety sheet)
DFO Synthesis Reference
No information avaliable
DFO Molecular Weight
343.463 g/mol
DFO Melting Point
99-101oC (HCl salt)
DFO H2O Solubility
42 mg/L
DFO State
Solid
DFO LogP
3.588
DFO Dosage Forms
Ointment
DFO Indication
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
DFO Pharmacology
Dibucaine is an amide-type local anesthetic, similar to lidocaine.
DFO Absorption
In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.
DFO side effects and Toxicity
Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
DFO Patient Information
No information avaliable
DFO Organisms Affected
Humans and other mammals
