Colesevelam hydrochloride
Brand names,
Colesevelam hydrochloride
Analogs
Colesevelam hydrochloride
Brand Names Mixture
Colesevelam hydrochloride
Chemical_Formula
C2H7NS
Colesevelam hydrochloride
RX_link
No information avaliable
Colesevelam hydrochloride
fda sheet
Colesevelam hydrochloride
msds (material safety sheet)
Colesevelam hydrochloride
Synthesis Reference
No information avaliable
Colesevelam hydrochloride
Molecular Weight
77.1497 g/mol
Colesevelam hydrochloride
Melting Point
98 oC
Colesevelam hydrochloride
H2O Solubility
No information avaliable
Colesevelam hydrochloride
State
Solid
Colesevelam hydrochloride
LogP
-0.196
Colesevelam hydrochloride
Dosage Forms
Capsule (50 mg, 150 mg)
Colesevelam hydrochloride
Indication
Given intravenously or orally to treat radiation sickness. The bitartrate has been used for the oral treatment of nephropathic cystinosis.
Colesevelam hydrochloride
Pharmacology
People born without the ability to metabolize the amino acid cystine suffer from cystinosis, a rare inherited disorder characterized by the deposition and accumulation of cystine crystals throughout the body. These crystals cause considerable damage, particularly in the kidney. Kidney failure can occur by the age of 10 in untreated patients. Cysteamine prevents the accumulation of cystine crystals and is prescribed to prevent further kidney damage. Cysteamine helps to convert cystine into less harmful chemical forms that can be removed from cells.
Colesevelam hydrochloride
Absorption
No information avaliable
Colesevelam hydrochloride
side effects and Toxicity
Symptoms of overdose may include convulsions (seizures), increased thirst and unusual tiredness or weakness.
Colesevelam hydrochloride
Patient Information
No information avaliable
Colesevelam hydrochloride
Organisms Affected
Humans and other mammals