Clopidogrel
Clopidogrel Brand names, Clopidogrel Analogs
Clopidogrel Brand Names Mixture
- No information avaliable
Clopidogrel Chemical_Formula
C16H16ClNO2S
Clopidogrel RX_link
http://www.rxlist.com/cgi/generic/clopidog.htm
Clopidogrel fda sheet
Clopidogrel msds (material safety sheet)
Clopidogrel Synthesis Reference
D. Aubert et al.; U.S. Pat. 4,529,596(1985)
Clopidogrel Molecular Weight
321.822 g/mol
Clopidogrel Melting Point
158oC
Clopidogrel H2O Solubility
50.78 mg/L
Clopidogrel State
solid
Clopidogrel LogP
No information avaliable
Clopidogrel Dosage Forms
Tablet (round, biconvex, film-coated)
Clopidogrel Indication
For the reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by recent stroke, recent myocardial infarction, or established peripheral arterial disease
Clopidogrel Pharmacology
Clopidogrel, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to reduce atherosclerotic events such as myocardial infarction, stroke, and vascular death in patients who have had a recent stroke, recent MI, or have established peripheral vascular disease.
Clopidogrel Absorption
Absorption is at least 50% based on urinary excretion of clopidogrel-related metabolites. Bioavailability has not been found to be affected by food.
Clopidogrel side effects and Toxicity
Symptoms of acute toxicity include vomiting (in baboons), prostration, difficult breathing, and gastrointestinal hemorrhage.
Clopidogrel Patient Information
Patients should be told that they may bleed more easily and it may take them longer than usual to stop bleeding when they take Plavix or Plavix combined with aspirin, and that they should report any unusual bleeding to their physician. Patients should inform physicians and dentists that they are taking Plavix and/or any other product known to affect bleeding before any surgery is scheduled and before any new drug is taken.
Clopidogrel Organisms Affected
Humans and other mammals
