Cerulenin
Cerulenin Brand names, Cerulenin Analogs
Cerulenin Brand Names Mixture
- No information avaliable
Cerulenin Chemical_Formula
C12H17NO3
Cerulenin RX_link
No information avaliable
Cerulenin fda sheet
Cerulenin msds (material safety sheet)
Cerulenin Synthesis Reference
No information avaliable
Cerulenin Molecular Weight
223.268 g/mol
Cerulenin Melting Point
93.5 oC
Cerulenin H2O Solubility
Slightly soluble
Cerulenin State
Solid
Cerulenin LogP
-0.147
Cerulenin Dosage Forms
No information avaliable
Cerulenin Indication
For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
Cerulenin Pharmacology
Cerulenin is an antifungal antibiotic isolated from Cephalosporium caerulens. It interrupts fungal growth by inhibiting the biosynthesis of sterols and fatty acids (inhibits bacterial fatty acid synthesis). It also inhibits HMG-CoA synthetase activity. Cerulenin produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors.
Cerulenin Absorption
No information avaliable
Cerulenin side effects and Toxicity
Oral, mouse LD50: 547 mg/kg. Symptoms of overexposure include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting, and headache.
Cerulenin Patient Information
No information avaliable
Cerulenin Organisms Affected
Humans, other mammals, fungi and bacteria
