Helicocerin
Brand names,
Helicocerin
Analogs
Helicocerin
Brand Names Mixture
Helicocerin
Chemical_Formula
C12H17NO3
Helicocerin
RX_link
No information avaliable
Helicocerin
fda sheet
Helicocerin
msds (material safety sheet)
Helicocerin
Synthesis Reference
No information avaliable
Helicocerin
Molecular Weight
223.268 g/mol
Helicocerin
Melting Point
93.5 oC
Helicocerin
H2O Solubility
Slightly soluble
Helicocerin
State
Solid
Helicocerin
LogP
-0.147
Helicocerin
Dosage Forms
No information avaliable
Helicocerin
Indication
For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
Helicocerin
Pharmacology
Cerulenin is an antifungal antibiotic isolated from Cephalosporium caerulens. It interrupts fungal growth by inhibiting the biosynthesis of sterols and fatty acids (inhibits bacterial fatty acid synthesis). It also inhibits HMG-CoA synthetase activity. Cerulenin produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors.
Helicocerin
Absorption
No information avaliable
Helicocerin
side effects and Toxicity
Oral, mouse LD50: 547 mg/kg. Symptoms of overexposure include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting, and headache.
Helicocerin
Patient Information
No information avaliable
Helicocerin
Organisms Affected
Humans, other mammals, fungi and bacteria