Cefotiamum [INN-Latin]
Brand names,
Cefotiamum [INN-Latin]
Analogs
Cefotiamum [INN-Latin]
Brand Names Mixture
Cefotiamum [INN-Latin]
Chemical_Formula
C18H23N9O4S3
Cefotiamum [INN-Latin]
RX_link
No information avaliable
Cefotiamum [INN-Latin]
fda sheet
Cefotiamum [INN-Latin]
msds (material safety sheet)
Cefotiamum [INN-Latin]
Synthesis Reference
No information avaliable
Cefotiamum [INN-Latin]
Molecular Weight
525.631 g/mol
Cefotiamum [INN-Latin]
Melting Point
No information avaliable
Cefotiamum [INN-Latin]
H2O Solubility
Soluble
Cefotiamum [INN-Latin]
State
Solid
Cefotiamum [INN-Latin]
LogP
-1.005
Cefotiamum [INN-Latin]
Dosage Forms
Injection and infusion
Cefotiamum [INN-Latin]
Indication
For treatment of severe infections caused by susceptible bacteria.
Cefotiamum [INN-Latin]
Pharmacology
Cefotiam is a third generation beta-lactam cephalosporin antibiotic. It has broad spectrum activity against Gram positive and Gram negative bacteria. It does not have activity against Pseudomonas aeruginosa. Cefotiam works by inhibiting bacterial cell wall biosynthesis.
Cefotiamum [INN-Latin]
Absorption
Rapidly absorbed following intramuscular injection. Bioavailability is 60% following intramuscular injection.
Cefotiamum [INN-Latin]
side effects and Toxicity
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Cefotiamum [INN-Latin]
Patient Information
No information avaliable
Cefotiamum [INN-Latin]
Organisms Affected
Enteric bacteria and other eubacteria