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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C18H23N9O4S3
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
525.631 g/mol
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Melting Point
No information avaliable
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H2O Solubility
Soluble
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State
Solid
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LogP
-1.005
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Dosage Forms
Injection and infusion
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Indication
For treatment of severe infections caused by susceptible bacteria.
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Pharmacology
Cefotiam is a third generation beta-lactam cephalosporin antibiotic. It has broad spectrum activity against Gram positive and Gram negative bacteria. It does not have activity against Pseudomonas aeruginosa. Cefotiam works by inhibiting bacterial cell wall biosynthesis.
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Absorption
Rapidly absorbed following intramuscular injection. Bioavailability is 60% following intramuscular injection.
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side effects and Toxicity
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
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Patient Information
No information avaliable
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Organisms Affected
Enteric bacteria and other eubacteria