Cefotiam hydrochloride
Brand names,
Cefotiam hydrochloride
Analogs
Cefotiam hydrochloride
Brand Names Mixture
Cefotiam hydrochloride
Chemical_Formula
C18H23N9O4S3
Cefotiam hydrochloride
RX_link
No information avaliable
Cefotiam hydrochloride
fda sheet
Cefotiam hydrochloride
msds (material safety sheet)
Cefotiam hydrochloride
Synthesis Reference
No information avaliable
Cefotiam hydrochloride
Molecular Weight
525.631 g/mol
Cefotiam hydrochloride
Melting Point
No information avaliable
Cefotiam hydrochloride
H2O Solubility
Soluble
Cefotiam hydrochloride
State
Solid
Cefotiam hydrochloride
LogP
-1.005
Cefotiam hydrochloride
Dosage Forms
Injection and infusion
Cefotiam hydrochloride
Indication
For treatment of severe infections caused by susceptible bacteria.
Cefotiam hydrochloride
Pharmacology
Cefotiam is a third generation beta-lactam cephalosporin antibiotic. It has broad spectrum activity against Gram positive and Gram negative bacteria. It does not have activity against Pseudomonas aeruginosa. Cefotiam works by inhibiting bacterial cell wall biosynthesis.
Cefotiam hydrochloride
Absorption
Rapidly absorbed following intramuscular injection. Bioavailability is 60% following intramuscular injection.
Cefotiam hydrochloride
side effects and Toxicity
Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Cefotiam hydrochloride
Patient Information
No information avaliable
Cefotiam hydrochloride
Organisms Affected
Enteric bacteria and other eubacteria