Caspofungin
Caspofungin Brand names, Caspofungin Analogs
Caspofungin Brand Names Mixture
- No information avaliable
Caspofungin Chemical_Formula
C52H88N10O15
Caspofungin RX_link
http://www.rxlist.com/cgi/generic/caspofungin.htm
Caspofungin fda sheet
Caspofungin msds (material safety sheet)
Caspofungin Synthesis Reference
No information avaliable
Caspofungin Molecular Weight
1093.31 g/mol
Caspofungin Melting Point
No information avaliable
Caspofungin H2O Solubility
No information avaliable
Caspofungin State
Solid
Caspofungin LogP
-2.798
Caspofungin Dosage Forms
Powder for solution
Caspofungin Indication
For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
Caspofungin Pharmacology
Caspofungin is an antifungal drug, and belongs to a new class termed the echinocandins. It is used to treat Aspergillus and Candida infection, and works by inhibiting cell wall synthesis. Antifungals in the echinocandin class inhibit the synthesis of glucan in the cell wall, probably via the enzyme 1,3-beta glucan synthase. There is a potential for resistance development to occur, however in vitro resistance development to Caspofungin by Aspergillus species has not been studied.
Caspofungin Absorption
92% tissue distribution within 36-48 hours after intravenous infusion
Caspofungin side effects and Toxicity
Side effects include rash, swelling, and nausea (rare)
Caspofungin Patient Information
No information avaliable
Caspofungin Organisms Affected
Aspergillis, Candida and other fungi
