Caspofungin
Brand names,
Caspofungin
Analogs
Caspofungin
Brand Names Mixture
Caspofungin
Chemical_Formula
C52H88N10O15
Caspofungin
RX_link
http://www.rxlist.com/cgi/generic/caspofungin.htm
Caspofungin
fda sheet
Caspofungin
msds (material safety sheet)
Caspofungin
Synthesis Reference
No information avaliable
Caspofungin
Molecular Weight
1093.31 g/mol
Caspofungin
Melting Point
No information avaliable
Caspofungin
H2O Solubility
No information avaliable
Caspofungin
State
Solid
Caspofungin
LogP
-2.798
Caspofungin
Dosage Forms
Powder for solution
Caspofungin
Indication
For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
Caspofungin
Pharmacology
Caspofungin is an antifungal drug, and belongs to a new class termed the echinocandins. It is used to treat Aspergillus and Candida infection, and works by inhibiting cell wall synthesis. Antifungals in the echinocandin class inhibit the synthesis of glucan in the cell wall, probably via the enzyme 1,3-beta glucan synthase. There is a potential for resistance development to occur, however in vitro resistance development to Caspofungin by Aspergillus species has not been studied.
Caspofungin
Absorption
92% tissue distribution within 36-48 hours after intravenous infusion
Caspofungin
side effects and Toxicity
Side effects include rash, swelling, and nausea (rare)
Caspofungin
Patient Information
No information avaliable
Caspofungin
Organisms Affected
Aspergillis, Candida and other fungi