Caspofungin acetate
Brand names,
Caspofungin acetate
Analogs
Caspofungin acetate
Brand Names Mixture
Caspofungin acetate
Chemical_Formula
C52H88N10O15
Caspofungin acetate
RX_link
http://www.rxlist.com/cgi/generic/caspofungin.htm
Caspofungin acetate
fda sheet
Caspofungin acetate
msds (material safety sheet)
Caspofungin acetate
Synthesis Reference
No information avaliable
Caspofungin acetate
Molecular Weight
1093.31 g/mol
Caspofungin acetate
Melting Point
No information avaliable
Caspofungin acetate
H2O Solubility
No information avaliable
Caspofungin acetate
State
Solid
Caspofungin acetate
LogP
-2.798
Caspofungin acetate
Dosage Forms
Powder for solution
Caspofungin acetate
Indication
For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
Caspofungin acetate
Pharmacology
Caspofungin is an antifungal drug, and belongs to a new class termed the echinocandins. It is used to treat Aspergillus and Candida infection, and works by inhibiting cell wall synthesis. Antifungals in the echinocandin class inhibit the synthesis of glucan in the cell wall, probably via the enzyme 1,3-beta glucan synthase. There is a potential for resistance development to occur, however in vitro resistance development to Caspofungin by Aspergillus species has not been studied.
Caspofungin acetate
Absorption
92% tissue distribution within 36-48 hours after intravenous infusion
Caspofungin acetate
side effects and Toxicity
Side effects include rash, swelling, and nausea (rare)
Caspofungin acetate
Patient Information
No information avaliable
Caspofungin acetate
Organisms Affected
Aspergillis, Candida and other fungi