Bivalirudin
Bivalirudin Brand names, Bivalirudin Analogs
Bivalirudin Brand Names Mixture
- Tavist-D Tablets (Clemastine + Phenylpropanolamine Hydrochloride)
Bivalirudin Chemical_Formula
C98H138N24O33
Bivalirudin RX_link
http://www.rxlist.com/cgi/generic/angiomax.htm
Bivalirudin fda sheet
Bivalirudin msds (material safety sheet)
Bivalirudin Synthesis Reference
No information avaliable
Bivalirudin Molecular Weight
2180.3
Bivalirudin Melting Point
No information avaliable
Bivalirudin H2O Solubility
No information avaliable
Bivalirudin State
Liquid
Bivalirudin LogP
-0.985
Bivalirudin Dosage Forms
Solution (IV Injection and Infusion)
Bivalirudin Indication
For treatment of heparin-induced thrombocytopenia
Bivalirudin Pharmacology
Angiomax directly inhibits thrombin by specifically binding both to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Thrombin is a serine proteinase that plays a central role in the thrombotic process, acting to cleave fibrinogen into fibrin monomers and to activate Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked framework which stabilizes the thrombus; thrombin also activates Factors V and VIII, promoting further thrombin generation, and activates platelets, stimulating aggregation and granule release
Bivalirudin Absorption
No information avaliable
Bivalirudin side effects and Toxicity
No information avaliable
Bivalirudin Patient Information
No information avaliable
Bivalirudin Organisms Affected
Humans and other mammals
