Angiomax
Brand names,
Angiomax
Analogs
Angiomax
Brand Names Mixture
- Tavist-D Tablets (Clemastine + Phenylpropanolamine Hydrochloride)
Angiomax
Chemical_Formula
C98H138N24O33
Angiomax
RX_link
http://www.rxlist.com/cgi/generic/angiomax.htm
Angiomax
fda sheet
Angiomax
msds (material safety sheet)
Angiomax
Synthesis Reference
No information avaliable
Angiomax
Molecular Weight
2180.3
Angiomax
Melting Point
No information avaliable
Angiomax
H2O Solubility
No information avaliable
Angiomax
State
Liquid
Angiomax
LogP
-0.985
Angiomax
Dosage Forms
Solution (IV Injection and Infusion)
Angiomax
Indication
For treatment of heparin-induced thrombocytopenia
Angiomax
Pharmacology
Angiomax directly inhibits thrombin by specifically binding both to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Thrombin is a serine proteinase that plays a central role in the thrombotic process, acting to cleave fibrinogen into fibrin monomers and to activate Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked framework which stabilizes the thrombus; thrombin also activates Factors V and VIII, promoting further thrombin generation, and activates platelets, stimulating aggregation and granule release
Angiomax
Absorption
No information avaliable
Angiomax
side effects and Toxicity
No information avaliable
Angiomax
Patient Information
No information avaliable
Angiomax
Organisms Affected
Humans and other mammals