Angiomax (Medicines Co or MDCO)
Angiomax (Medicines Co or MDCO) Brand names, Angiomax (Medicines Co or MDCO) Analogs
Angiomax (Medicines Co or MDCO) Brand Names Mixture
- Tavist-D Tablets (Clemastine + Phenylpropanolamine Hydrochloride)
Angiomax (Medicines Co or MDCO) Chemical_Formula
C98H138N24O33
Angiomax (Medicines Co or MDCO) RX_link
http://www.rxlist.com/cgi/generic/angiomax.htm
Angiomax (Medicines Co or MDCO) fda sheet
Angiomax (Medicines Co or MDCO) msds (material safety sheet)
Angiomax (Medicines Co or MDCO) Synthesis Reference
No information avaliable
Angiomax (Medicines Co or MDCO) Molecular Weight
2180.3
Angiomax (Medicines Co or MDCO) Melting Point
No information avaliable
Angiomax (Medicines Co or MDCO) H2O Solubility
No information avaliable
Angiomax (Medicines Co or MDCO) State
Liquid
Angiomax (Medicines Co or MDCO) LogP
-0.985
Angiomax (Medicines Co or MDCO) Dosage Forms
Solution (IV Injection and Infusion)
Angiomax (Medicines Co or MDCO) Indication
For treatment of heparin-induced thrombocytopenia
Angiomax (Medicines Co or MDCO) Pharmacology
Angiomax directly inhibits thrombin by specifically binding both to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Thrombin is a serine proteinase that plays a central role in the thrombotic process, acting to cleave fibrinogen into fibrin monomers and to activate Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked framework which stabilizes the thrombus; thrombin also activates Factors V and VIII, promoting further thrombin generation, and activates platelets, stimulating aggregation and granule release
Angiomax (Medicines Co or MDCO) Absorption
No information avaliable
Angiomax (Medicines Co or MDCO) side effects and Toxicity
No information avaliable
Angiomax (Medicines Co or MDCO) Patient Information
No information avaliable
Angiomax (Medicines Co or MDCO) Organisms Affected
Humans and other mammals
