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Balsalazide Brand names, Balsalazide Analogs

Balsalazide Brand Names Mixture

  • No information avaliable

Balsalazide Chemical_Formula


Balsalazide RX_link

Balsalazide fda sheet

Balsalazide FDA

Balsalazide msds (material safety sheet)

Balsalazide Synthesis Reference

No information avaliable

Balsalazide Molecular Weight

357.318 g/mol

Balsalazide Melting Point

No information avaliable

Balsalazide H2O Solubility

Freely soluble as disodium salt

Balsalazide State


Balsalazide LogP


Balsalazide Dosage Forms

Capsule (750 mg)

Balsalazide Indication

For the treatment of mildly to moderately active ulcerative colitis.

Balsalazide Pharmacology

Balsalazide is a prodrug that is enzymatically cleaved in the colon to produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug indicated for the treatment of mildly to moderately active ulcerative colitis. Balsalazide disodium is delivered intact to the colon where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, which is the therapeutically active portion of the molecule, and 4-aminobenzoyl-(beta)-alanine.

Balsalazide Absorption

Low and variable, intact balsalazide is poorly absorbed systemically.

Balsalazide side effects and Toxicity

A single oral dose of balsalazide disodium at 5 grams/kg or 4-aminobenzoyl-(beta)-alanine, a metabolite of balsalazide disodium, at 1 gram/kg was non-lethal in mice and rats. No symptoms of acute toxicity were seen at these doses.

Balsalazide Patient Information

No information avaliable

Balsalazide Organisms Affected

Humans and other mammals