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Colazal Brand names, Colazal Analogs

Colazal Brand Names Mixture

  • No information avaliable

Colazal Chemical_Formula


Colazal RX_link

Colazal fda sheet

Colazal FDA

Colazal msds (material safety sheet)

Colazal Synthesis Reference

No information avaliable

Colazal Molecular Weight

357.318 g/mol

Colazal Melting Point

No information avaliable

Colazal H2O Solubility

Freely soluble as disodium salt

Colazal State


Colazal LogP


Colazal Dosage Forms

Capsule (750 mg)

Colazal Indication

For the treatment of mildly to moderately active ulcerative colitis.

Colazal Pharmacology

Balsalazide is a prodrug that is enzymatically cleaved in the colon to produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug indicated for the treatment of mildly to moderately active ulcerative colitis. Balsalazide disodium is delivered intact to the colon where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, which is the therapeutically active portion of the molecule, and 4-aminobenzoyl-(beta)-alanine.

Colazal Absorption

Low and variable, intact balsalazide is poorly absorbed systemically.

Colazal side effects and Toxicity

A single oral dose of balsalazide disodium at 5 grams/kg or 4-aminobenzoyl-(beta)-alanine, a metabolite of balsalazide disodium, at 1 gram/kg was non-lethal in mice and rats. No symptoms of acute toxicity were seen at these doses.

Colazal Patient Information

No information avaliable

Colazal Organisms Affected

Humans and other mammals