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Carbadox Brand names, Carbadox Analogs

Carbadox Brand Names Mixture

  • No information avaliable

Carbadox Chemical_Formula


Carbadox RX_link

Carbadox fda sheet

Carbadox FDA

Carbadox msds (material safety sheet)

Carbadox Synthesis Reference

No information avaliable

Carbadox Molecular Weight

357.318 g/mol

Carbadox Melting Point

No information avaliable

Carbadox H2O Solubility

Freely soluble as disodium salt

Carbadox State


Carbadox LogP


Carbadox Dosage Forms

Capsule (750 mg)

Carbadox Indication

For the treatment of mildly to moderately active ulcerative colitis.

Carbadox Pharmacology

Balsalazide is a prodrug that is enzymatically cleaved in the colon to produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug indicated for the treatment of mildly to moderately active ulcerative colitis. Balsalazide disodium is delivered intact to the colon where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, which is the therapeutically active portion of the molecule, and 4-aminobenzoyl-(beta)-alanine.

Carbadox Absorption

Low and variable, intact balsalazide is poorly absorbed systemically.

Carbadox side effects and Toxicity

A single oral dose of balsalazide disodium at 5 grams/kg or 4-aminobenzoyl-(beta)-alanine, a metabolite of balsalazide disodium, at 1 gram/kg was non-lethal in mice and rats. No symptoms of acute toxicity were seen at these doses.

Carbadox Patient Information

No information avaliable

Carbadox Organisms Affected

Humans and other mammals