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Asacolitin Brand names, Asacolitin Analogs

Asacolitin Brand Names Mixture

  • No information avaliable

Asacolitin Chemical_Formula


Asacolitin RX_link

No information avaliable

Asacolitin fda sheet

Asacolitin FDA

Asacolitin msds (material safety sheet)

Asacolitin Synthesis Reference

No information avaliable

Asacolitin Molecular Weight

145.156 g/mol

Asacolitin Melting Point

No information avaliable

Asacolitin H2O Solubility

Freely soluble

Asacolitin State


Asacolitin LogP


Asacolitin Dosage Forms

Cream for topical administration (160 mg/g of methyl aminolevulinate equivalent to 16.0% of methyl aminolevulinate)

Asacolitin Indication

For topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).

Asacolitin Pharmacology

After topical application of methyl aminolevulinate, porphyrins will accumulate intracellularly in the treated skin lesions. The intracellular porphyrins (including PpIX) are photoactive, fluorescing compounds and, upon light activation in the presence of oxygen, singlet oxygen is formed which causes damage to cellular compartments, in particular the mitochondria. Light activation of accumulated porphyrins leads to a photochemical reaction and thereby phototoxicity to the light-exposed target cells.

Asacolitin Absorption

In vitro, after 24 hours the mean cumulative absorption through human skin was 0.26% of the administered dose.

Asacolitin side effects and Toxicity

The severity of local phototoxic reactions such as erythema, pain and burning sensation may increase in case of prolonged application time or very high light intensity.

Asacolitin Patient Information

Asacolitin Organisms Affected

Humans and other mammals