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Asacol Brand names, Asacol Analogs

Asacol Brand Names Mixture

  • No information avaliable

Asacol Chemical_Formula

C6H11NO3

Asacol RX_link

No information avaliable

Asacol fda sheet

Asacol FDA

Asacol msds (material safety sheet)

Asacol Synthesis Reference

No information avaliable

Asacol Molecular Weight

145.156 g/mol

Asacol Melting Point

No information avaliable

Asacol H2O Solubility

Freely soluble

Asacol State

Solid

Asacol LogP

-1.026

Asacol Dosage Forms

Cream for topical administration (160 mg/g of methyl aminolevulinate equivalent to 16.0% of methyl aminolevulinate)

Asacol Indication

For topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).

Asacol Pharmacology

After topical application of methyl aminolevulinate, porphyrins will accumulate intracellularly in the treated skin lesions. The intracellular porphyrins (including PpIX) are photoactive, fluorescing compounds and, upon light activation in the presence of oxygen, singlet oxygen is formed which causes damage to cellular compartments, in particular the mitochondria. Light activation of accumulated porphyrins leads to a photochemical reaction and thereby phototoxicity to the light-exposed target cells.

Asacol Absorption

In vitro, after 24 hours the mean cumulative absorption through human skin was 0.26% of the administered dose.

Asacol side effects and Toxicity

The severity of local phototoxic reactions such as erythema, pain and burning sensation may increase in case of prolonged application time or very high light intensity.

Asacol Patient Information

Asacol Organisms Affected

Humans and other mammals