Aminohippurate en es it fr

Aminohippurate Brand names, Aminohippurate Analogs

Aminohippurate Brand Names Mixture

  • No information avaliable

Aminohippurate Chemical_Formula


Aminohippurate RX_link

Aminohippurate fda sheet

Aminohippurate msds (material safety sheet)

Aminohippurate MSDS

Aminohippurate Synthesis Reference

No information avaliable

Aminohippurate Molecular Weight

194.187 g/mol

Aminohippurate Melting Point

199-200 oC

Aminohippurate H2O Solubility

Slightly soluble

Aminohippurate State


Aminohippurate LogP


Aminohippurate Dosage Forms

Solution for injection (1g drug per 5mL solution)

Aminohippurate Indication

Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.

Aminohippurate Pharmacology

Aminohippurate (p-aminohippuric acid, PAH, PAHA) is the glycine amide of p-aminobenzoic acid. It is filtered by the glomeruli and is actively secreted by the proximal tubules. At low plasma concentrations (1.0 to 2.0 mg/100 mL), an average of 90 percent of aminohippurate is cleared by the kidneys from the renal blood stream in a single circulation. It is ideally suited for measurement of ERPF since it has a high clearance, is essentially nontoxic at the plasma concentrations reached with recommended doses, and its analytical determination is relatively simple and accurate. Aminohippurate is also used to measure the functional capacity of the renal tubular secretory mechanism or transport maximum (TmPAH). This is accomplished by elevating the plasma concentration to levels (40-60 mg/100 mL) sufficient to saturate the maximal capacity of the tubular cells to secrete aminohippurate. Inulin clearance is generally measured during TmPAH determinations since glomerular filtration rate (GFR) must be known before calculations of secretory Tm measurements can be done.

Aminohippurate Absorption

No information avaliable

Aminohippurate side effects and Toxicity

No information avaliable

Aminohippurate Patient Information

Aminohippurate Organisms Affected

Humans and other mammals