Aminohippuric acid Sodium salt en es it fr

Aminohippuric acid Sodium salt Brand names, Aminohippuric acid Sodium salt Analogs

Aminohippuric acid Sodium salt Brand Names Mixture

  • No information avaliable

Aminohippuric acid Sodium salt Chemical_Formula

C9H10N2O3

Aminohippuric acid Sodium salt RX_link

http://www.rxlist.com/cgi/generic2/aminohippurate.htm

Aminohippuric acid Sodium salt fda sheet

Aminohippuric acid Sodium salt msds (material safety sheet)

Aminohippuric_acid_Sodium_salt MSDS

Aminohippuric acid Sodium salt Synthesis Reference

No information avaliable

Aminohippuric acid Sodium salt Molecular Weight

194.187 g/mol

Aminohippuric acid Sodium salt Melting Point

199-200 oC

Aminohippuric acid Sodium salt H2O Solubility

Slightly soluble

Aminohippuric acid Sodium salt State

Solid

Aminohippuric acid Sodium salt LogP

-0.052

Aminohippuric acid Sodium salt Dosage Forms

Solution for injection (1g drug per 5mL solution)

Aminohippuric acid Sodium salt Indication

Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.

Aminohippuric acid Sodium salt Pharmacology

Aminohippurate (p-aminohippuric acid, PAH, PAHA) is the glycine amide of p-aminobenzoic acid. It is filtered by the glomeruli and is actively secreted by the proximal tubules. At low plasma concentrations (1.0 to 2.0 mg/100 mL), an average of 90 percent of aminohippurate is cleared by the kidneys from the renal blood stream in a single circulation. It is ideally suited for measurement of ERPF since it has a high clearance, is essentially nontoxic at the plasma concentrations reached with recommended doses, and its analytical determination is relatively simple and accurate. Aminohippurate is also used to measure the functional capacity of the renal tubular secretory mechanism or transport maximum (TmPAH). This is accomplished by elevating the plasma concentration to levels (40-60 mg/100 mL) sufficient to saturate the maximal capacity of the tubular cells to secrete aminohippurate. Inulin clearance is generally measured during TmPAH determinations since glomerular filtration rate (GFR) must be known before calculations of secretory Tm measurements can be done.

Aminohippuric acid Sodium salt Absorption

No information avaliable

Aminohippuric acid Sodium salt side effects and Toxicity

No information avaliable

Aminohippuric acid Sodium salt Patient Information

Aminohippuric acid Sodium salt Organisms Affected

Humans and other mammals