Aminohippuric acid en es it fr

Aminohippuric acid Brand names, Aminohippuric acid Analogs

Aminohippuric acid Brand Names Mixture

  • No information avaliable

Aminohippuric acid Chemical_Formula


Aminohippuric acid RX_link

Aminohippuric acid fda sheet

Aminohippuric acid msds (material safety sheet)

Aminohippuric_acid MSDS

Aminohippuric acid Synthesis Reference

No information avaliable

Aminohippuric acid Molecular Weight

194.187 g/mol

Aminohippuric acid Melting Point

199-200 oC

Aminohippuric acid H2O Solubility

Slightly soluble

Aminohippuric acid State


Aminohippuric acid LogP


Aminohippuric acid Dosage Forms

Solution for injection (1g drug per 5mL solution)

Aminohippuric acid Indication

Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.

Aminohippuric acid Pharmacology

Aminohippurate (p-aminohippuric acid, PAH, PAHA) is the glycine amide of p-aminobenzoic acid. It is filtered by the glomeruli and is actively secreted by the proximal tubules. At low plasma concentrations (1.0 to 2.0 mg/100 mL), an average of 90 percent of aminohippurate is cleared by the kidneys from the renal blood stream in a single circulation. It is ideally suited for measurement of ERPF since it has a high clearance, is essentially nontoxic at the plasma concentrations reached with recommended doses, and its analytical determination is relatively simple and accurate. Aminohippurate is also used to measure the functional capacity of the renal tubular secretory mechanism or transport maximum (TmPAH). This is accomplished by elevating the plasma concentration to levels (40-60 mg/100 mL) sufficient to saturate the maximal capacity of the tubular cells to secrete aminohippurate. Inulin clearance is generally measured during TmPAH determinations since glomerular filtration rate (GFR) must be known before calculations of secretory Tm measurements can be done.

Aminohippuric acid Absorption

No information avaliable

Aminohippuric acid side effects and Toxicity

No information avaliable

Aminohippuric acid Patient Information

Aminohippuric acid Organisms Affected

Humans and other mammals