Amgen) en es it fr

Amgen) Brand names, Amgen) Analogs

Amgen) Brand Names Mixture

  • No information avaliable

Amgen) Chemical_Formula


Amgen) RX_link

Amgen) fda sheet

Amgen) msds (material safety sheet)

Amgen) Synthesis Reference

No information avaliable

Amgen) Molecular Weight


Amgen) Melting Point

61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999))Davis JM, Narachi MA, Levine HL, Alton NK, Arakawa T. Conformation and stability of two recombinant human interferon-alpha analogs.

Amgen) H2O Solubility

No information avaliable

Amgen) State


Amgen) LogP


Amgen) Dosage Forms


Amgen) Indication

For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma

Amgen) Pharmacology

Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R.

Amgen) Absorption

No information avaliable

Amgen) side effects and Toxicity

No information avaliable

Amgen) Patient Information


Amgen) Organisms Affected

No information avaliable