Infergen (InterMune Inc
Infergen (InterMune Inc Brand names, Infergen (InterMune Inc Analogs
Infergen (InterMune Inc Brand Names Mixture
- No information avaliable
Infergen (InterMune Inc Chemical_Formula
C860H1353N227O255S9
Infergen (InterMune Inc RX_link
http://www.rxlist.com/cgi/generic2/infergen.htm
Infergen (InterMune Inc fda sheet
Infergen (InterMune Inc msds (material safety sheet)
Infergen (InterMune Inc Synthesis Reference
No information avaliable
Infergen (InterMune Inc Molecular Weight
19343
Infergen (InterMune Inc Melting Point
61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999))Davis JM, Narachi MA, Levine HL, Alton NK, Arakawa T. Conformation and stability of two recombinant human interferon-alpha analogs.
Infergen (InterMune Inc H2O Solubility
No information avaliable
Infergen (InterMune Inc State
Liquid
Infergen (InterMune Inc LogP
-0.336
Infergen (InterMune Inc Dosage Forms
Solution
Infergen (InterMune Inc Indication
For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma
Infergen (InterMune Inc Pharmacology
Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R.
Infergen (InterMune Inc Absorption
No information avaliable
Infergen (InterMune Inc side effects and Toxicity
No information avaliable
Infergen (InterMune Inc Patient Information
BIOD00062.html
Infergen (InterMune Inc Organisms Affected
No information avaliable
