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Infergen (InterMune Inc Brand names, Infergen (InterMune Inc Analogs

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Infergen (InterMune Inc Chemical_Formula


Infergen (InterMune Inc RX_link

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Infergen (InterMune Inc Molecular Weight


Infergen (InterMune Inc Melting Point

61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999))Davis JM, Narachi MA, Levine HL, Alton NK, Arakawa T. Conformation and stability of two recombinant human interferon-alpha analogs.

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Infergen (InterMune Inc Indication

For treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma

Infergen (InterMune Inc Pharmacology

Upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Interferon alpha also induce the synthesis of several key antiviral mediators, including 2'-5' oligoadenylate synthetase (2'-5' A synthetase) and protein kinase R.

Infergen (InterMune Inc Absorption

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