Alfentanyl
Brand names,
Alfentanyl
Analogs
Alfentanyl
Brand Names Mixture
Alfentanyl
Chemical_Formula
C21H32N6O3
Alfentanyl
RX_link
http://www.rxlist.com/cgi/generic2/alfent.htm
Alfentanyl
fda sheet
Alfentanyl
msds (material safety sheet)
Alfentanyl
Synthesis Reference
No information avaliable
Alfentanyl
Molecular Weight
416.517 g/mol
Alfentanyl
Melting Point
140.8 oC
Alfentanyl
H2O Solubility
34.6 mg/L
Alfentanyl
State
Solid
Alfentanyl
LogP
0.006
Alfentanyl
Dosage Forms
Solution; Injection
Alfentanyl
Indication
For the management of postoperative pain and the maintenance of general anesthesia.
Alfentanyl
Pharmacology
Alfentanil is a synthetic opioid analgesic. Alfentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, alfentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Alfentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Alfentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Alfentanyl
Absorption
No information avaliable
Alfentanyl
side effects and Toxicity
Symptoms of overexposure include characteristic rigidity of the skeletal muscles, cardiac and respiratory depression, and narrowing of the pupils.
Alfentanyl
Patient Information
Alfentanyl
Organisms Affected
Humans and other mammals