JANSSEN PHARMACEUTICA INC -- ALFENTANIL HYDROCHLORIDE -- 6505-01-265-0009
===================== Product Identification =====================
Product ID:ALFENTANIL HYDROCHLORIDE
MSDS Date:07/01/1992
FSC:6505
NIIN:01-265-0009
MSDS Number: BXPCK
=== Responsible Party ===
Company Name:JANSSEN PHARMACEUTICA INC
Address:1125 TRENTON-HARBOURTON RD
City:TITUSVILLE
State:NJ
ZIP:08560-0200
Country:US
Info Phone Num:609-730-2142
Emergency Phone Num:609-730-2142
CAGE:GO500
=== Contractor Identification ===
Company Name:JANSSEN PHARMACEUTICA INC
Box:UNKNOW
CAGE:59484
Company Name:JANSSEN PHARMACEUTICAIAAN 3
Address:2440
City:GEAL
Country:US
Phone:800-227-6701
CAGE:GO500
============= Composition/Information on Ingredients =============
Ingred Name:ALFENTANIL HYDROCHLORIDE *95-1*
CAS:69049-06-5
RTECS #:TX1452500
===================== Hazards Identification =====================
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:CHARACTERISTIC RIGIDITY OF THE
SKELETAL MUSCLES, CARDIAC & RESPIRATORY DEPRESSION, NARROWING OF
THE PUPILS, CONSEQUENCES: LOWING OF BODY TEMP, COMA & DEATH. THIS
SUBSTANCE IS A POTENT, VERY RAPIDLY & SHORT ACTING ANALGESIC. VERY
SHORT-ACTING & POTENT MORPHINE-LIKE ANALGESIC (PAINKILLER).
Explanation of Carcinogenicity:NONE
Effects of Overexposure:CHARACTERISTIC RIGIDITY OF THE SKELETAL
MUSCLES, CARDIAC & RESPIRATORY DEPRESSION, NARROWING OF THE PUPILS,
CONSEQUENCES: LOWING OF BODY TEMP, COMA & DEATH. NOTE TO PHYSICIAN:
SPECIFIC ANTIDOTE-NALORP HINE HYDROBROMIDE: 5-10 MG I.V.,I.M/S.C.
IF NEEDED REPEAT 10-15 MIN LATER UP TO 40 MG. (SEE SUPP)
======================= First Aid Measures =======================
First Aid:INGESTION: RINSE MOUTH W/WATER. EYES: RINSE THOROUGHLY
W/RUNNING WATER FOR 10-15 MINS. SKIN: WASH W/WATER & SOAP.
INHALATION: IMMEDIATELY REMOVE TO FRESH AIR. GIVE CPR IF NEEDED.
KEEP WARM & QUIET. OB TAIN MEDICAL ATTENTION IN ALL CASES.
===================== Fire Fighting Measures =====================
Extinguishing Media:WATER, POWDER, HALONES, CO2, SAND, FOAM
Fire Fighting Procedures:WEAR GLOVES, PROTECTIVE CLOTHING & RESPIRATORY
PROTECTION. COOL CONTAINERS W/ATOMIZED WATER.
Unusual Fire/Explosion Hazard:AVOID DISPERSION OF THE PRODUCT.
================== Accidental Release Measures ==================
Spill Release Procedures:UPON RUPTURE, CAREFULLY COLLECT & SCOOP UP
PRODUCT & STORE IN A CLOSED CONTAINER FOR DESTRUCTION AS CHEMICAL
WASTE. WHEN CLEANING UP, ALWAYS WEAR SUITABLE GLOVES/DISPOSABLE
CLOTHES W/HOOD & COMPRESSED AIR MASK /HOOD, BREATHE EASY
5/EQUIVALENTS.(SUPP)
====================== Handling and Storage ======================
Handling and Storage Precautions:IMMEDIATELY TAKE OFF CONTAMINATED
CLOTHING. WEAR SUITABLE RESPIRATORY EQUIPMENT.
Other Precautions:AVOID CONTACT W/SKIN. WEAR SUITABLE PROTECTIVE
CLOTHING & GLOVES & RESPIRATORY EQUIPMENT. AVOID DISPERSION OF THE
PRODUCT.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:SMALL: USE GAS MASK W/P3 DUST FILTER. OTHER:
COMPRESSED-AIR MASK/HOOD/BREATHE-EASY 5 NO DISPOSABLE MASK.
Protective Gloves:DISPOSABLE
Eye Protection:NO DISPOSABLE MASK
Other Protective Equipment:CLOSED WORKING/DISPOSABLE CLOTHES W/HOOD
OVER ENTIRE WORKING CLOTHES.
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE. WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
SPILL CONT'D: UPON DISPERSION OF THE PRODUCT, FIRST DEMARCATE THE
ENVIRONMENT BEFORE STARTING TO CLEAN UP. COLLECT THE DISPOSABLE
CLOTHES IN A PLASTIC BAG FOR DESTRUCTION. IMMEDIATELY NOTIFY THE
SUPER VISOR. HEALTH HAZARDS CONT'D: NALOXONE HYDROCHLORIDE-400 UG
S.C., I.V./I.M., IF NEEDED REPEAT AFTER 2-3 MINS.
================== Physical/Chemical Properties ==================
Melt/Freeze Pt:M.P/F.P Text:275-284F
pH:3.6
Solubility in Water:130 G/L
Appearance and Odor:WHITE POWDER
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
OXIDANTS, REDUCING AGENTS, ALKALINES
Hazardous Decomposition Products:NITROUS OXIDES, CHLORINE, HYDROGEN
CHLORIDE, CO
Conditions to Avoid Polymerization:GROUND
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS. UN: 2811.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.