Alfenta
Brand names,
Alfenta
Analogs
Alfenta
Brand Names Mixture
Alfenta
Chemical_Formula
C21H32N6O3
Alfenta
RX_link
http://www.rxlist.com/cgi/generic2/alfent.htm
Alfenta
fda sheet
Alfenta
msds (material safety sheet)
Alfenta
Synthesis Reference
No information avaliable
Alfenta
Molecular Weight
416.517 g/mol
Alfenta
Melting Point
140.8 oC
Alfenta
H2O Solubility
34.6 mg/L
Alfenta
State
Solid
Alfenta
LogP
0.006
Alfenta
Dosage Forms
Solution; Injection
Alfenta
Indication
For the management of postoperative pain and the maintenance of general anesthesia.
Alfenta
Pharmacology
Alfentanil is a synthetic opioid analgesic. Alfentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, alfentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Alfentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Alfentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Alfenta
Absorption
No information avaliable
Alfenta
side effects and Toxicity
Symptoms of overexposure include characteristic rigidity of the skeletal muscles, cardiac and respiratory depression, and narrowing of the pupils.
Alfenta
Patient Information
Alfenta
Organisms Affected
Humans and other mammals