Alfentanil
Brand names,
Alfentanil
Analogs
Alfentanil
Brand Names Mixture
Alfentanil
Chemical_Formula
C21H32N6O3
Alfentanil
RX_link
http://www.rxlist.com/cgi/generic2/alfent.htm
Alfentanil
fda sheet
Alfentanil
msds (material safety sheet)
Alfentanil
Synthesis Reference
No information avaliable
Alfentanil
Molecular Weight
416.517 g/mol
Alfentanil
Melting Point
140.8 oC
Alfentanil
H2O Solubility
34.6 mg/L
Alfentanil
State
Solid
Alfentanil
LogP
0.006
Alfentanil
Dosage Forms
Solution; Injection
Alfentanil
Indication
For the management of postoperative pain and the maintenance of general anesthesia.
Alfentanil
Pharmacology
Alfentanil is a synthetic opioid analgesic. Alfentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, alfentanil exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Alfentanil may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Alfentanil depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Alfentanil
Absorption
No information avaliable
Alfentanil
side effects and Toxicity
Symptoms of overexposure include characteristic rigidity of the skeletal muscles, cardiac and respiratory depression, and narrowing of the pupils.
Alfentanil
Patient Information
Alfentanil
Organisms Affected
Humans and other mammals