Alemtuzumab
Alemtuzumab Brand names, Alemtuzumab Analogs
Alemtuzumab Brand Names Mixture
- Locacorten Vioform (Clioquinol + Flumethasone Pivalate)
- Locacorten Vioform Cream (Clioquinol + Flumethasone Pivalate)
- Locacorten Vioform Eardrops (Clioquinol + Flumethasone Pivalate)
- Locasalen (Flumethasone Pivalate + Salicylic Acid)
Alemtuzumab Chemical_Formula
C6468H10066N1732O2005S40
Alemtuzumab RX_link
http://www.rxlist.com/cgi/generic/campath.htm
Alemtuzumab fda sheet
Alemtuzumab msds (material safety sheet)
Alemtuzumab Synthesis Reference
No information avaliable
Alemtuzumab Molecular Weight
145453.8
Alemtuzumab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) ??“ Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Alemtuzumab H2O Solubility
No information avaliable
Alemtuzumab State
Liquid
Alemtuzumab LogP
-0.431
Alemtuzumab Dosage Forms
No information avaliable
Alemtuzumab Indication
For treatment of B-cell chronic lymphocytic leukemia
Alemtuzumab Pharmacology
Campath is used to treat leukemia by exploiting antibody mediated lysis of CD52 presenting cells. The CD52 antigen is a cell surface protein found on essentially all B and T lymphocytes, a majority of monocytes, macrophages and most granulocytes. The CD52 antigen is not present on erythrocytes or hematopoetic stem cells. In leukemia there is an excess of B and T cells, so Campath permits selective reduction of lymphocyte populations.
Alemtuzumab Absorption
No information avaliable
Alemtuzumab side effects and Toxicity
No information avaliable
Alemtuzumab Patient Information
No information avaliable
Alemtuzumab Organisms Affected
No information avaliable
