Campath
Brand names,
Campath
Analogs
Campath
Brand Names Mixture
- Locacorten Vioform (Clioquinol + Flumethasone Pivalate)
- Locacorten Vioform Cream (Clioquinol + Flumethasone Pivalate)
- Locacorten Vioform Eardrops (Clioquinol + Flumethasone Pivalate)
- Locasalen (Flumethasone Pivalate + Salicylic Acid)
Campath
Chemical_Formula
C6468H10066N1732O2005S40
Campath
RX_link
http://www.rxlist.com/cgi/generic/campath.htm
Campath
fda sheet
Campath
msds (material safety sheet)
Campath
Synthesis Reference
No information avaliable
Campath
Molecular Weight
145453.8
Campath
Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) ??“ Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Campath
H2O Solubility
No information avaliable
Campath
State
Liquid
Campath
LogP
-0.431
Campath
Dosage Forms
No information avaliable
Campath
Indication
For treatment of B-cell chronic lymphocytic leukemia
Campath
Pharmacology
Campath is used to treat leukemia by exploiting antibody mediated lysis of CD52 presenting cells. The CD52 antigen is a cell surface protein found on essentially all B and T lymphocytes, a majority of monocytes, macrophages and most granulocytes. The CD52 antigen is not present on erythrocytes or hematopoetic stem cells. In leukemia there is an excess of B and T cells, so Campath permits selective reduction of lymphocyte populations.
Campath
Absorption
No information avaliable
Campath
side effects and Toxicity
No information avaliable
Campath
Patient Information
No information avaliable
Campath
Organisms Affected
No information avaliable