Campath (ILEX Pharmaceuticals LP)
Brand names,
Campath (ILEX Pharmaceuticals LP)
Analogs
Campath (ILEX Pharmaceuticals LP)
Brand Names Mixture
- Locacorten Vioform (Clioquinol + Flumethasone Pivalate)
- Locacorten Vioform Cream (Clioquinol + Flumethasone Pivalate)
- Locacorten Vioform Eardrops (Clioquinol + Flumethasone Pivalate)
- Locasalen (Flumethasone Pivalate + Salicylic Acid)
Campath (ILEX Pharmaceuticals LP)
Chemical_Formula
C6468H10066N1732O2005S40
Campath (ILEX Pharmaceuticals LP)
RX_link
http://www.rxlist.com/cgi/generic/campath.htm
Campath (ILEX Pharmaceuticals LP)
fda sheet
Campath (ILEX Pharmaceuticals LP)
msds (material safety sheet)
Campath (ILEX Pharmaceuticals LP)
Synthesis Reference
No information avaliable
Campath (ILEX Pharmaceuticals LP)
Molecular Weight
145453.8
Campath (ILEX Pharmaceuticals LP)
Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) ??“ Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Campath (ILEX Pharmaceuticals LP)
H2O Solubility
No information avaliable
Campath (ILEX Pharmaceuticals LP)
State
Liquid
Campath (ILEX Pharmaceuticals LP)
LogP
-0.431
Campath (ILEX Pharmaceuticals LP)
Dosage Forms
No information avaliable
Campath (ILEX Pharmaceuticals LP)
Indication
For treatment of B-cell chronic lymphocytic leukemia
Campath (ILEX Pharmaceuticals LP)
Pharmacology
Campath is used to treat leukemia by exploiting antibody mediated lysis of CD52 presenting cells. The CD52 antigen is a cell surface protein found on essentially all B and T lymphocytes, a majority of monocytes, macrophages and most granulocytes. The CD52 antigen is not present on erythrocytes or hematopoetic stem cells. In leukemia there is an excess of B and T cells, so Campath permits selective reduction of lymphocyte populations.
Campath (ILEX Pharmaceuticals LP)
Absorption
No information avaliable
Campath (ILEX Pharmaceuticals LP)
side effects and Toxicity
No information avaliable
Campath (ILEX Pharmaceuticals LP)
Patient Information
No information avaliable
Campath (ILEX Pharmaceuticals LP)
Organisms Affected
No information avaliable