Albendazole
Albendazole Brand names, Albendazole Analogs
Albendazole Brand Names Mixture
- No information avaliable
Albendazole Chemical_Formula
C12H15N3O2S
Albendazole RX_link
http://www.rxlist.com/cgi/generic2/albendazole.htm
Albendazole fda sheet
Albendazole msds (material safety sheet)
Albendazole Synthesis Reference
No information avaliable
Albendazole Molecular Weight
265.333 g/mol
Albendazole Melting Point
209 oC
Albendazole H2O Solubility
Practically insoluble
Albendazole State
Solid
Albendazole LogP
3.299
Albendazole Dosage Forms
Suspension; Tablets (200mg)
Albendazole Indication
For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Albendazole Pharmacology
Albendazole is a broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.
Albendazole Absorption
Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g)
Albendazole side effects and Toxicity
Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.
Albendazole Patient Information
Albendazole Organisms Affected
Helminthic Microorganisms
